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CAS 9004-65-3 · E464 EINECS 618-389-1

HPMC Hydroxipropylmetylcellulosa

Definition, Chemistry, and Industrial Role — a complete reference for formulators across construction, pharma, food, personal care, and industrial sectors.

HPMC is a water-soluble, non-ionic cellulose ether produced by chemically modifying natural cellulose derived from wood pulp or cotton linter. It delivers multiple functional benefits — water retention, thickening, film forming, binding, and workability improvement — within a single versatile ingredient.

~ Snabbreferens ~
Fullständigt namn Hydroxipropylmetylcellulosa
CAS-nummer 9004-65-3
Livsmedelskod cURL Too many subrequests by single Worker invocation. To configure this limit, refer to https://developers.cloudflare.com/workers/wrangler/configuration/#limits
Iontyp Icke-jonisk
Löslighet Cold water soluble
Pharma Name Hypromellose
Utseende Vitt till benvitt pulver
Kemi
Cellulose ether chemistry lab
DS·MS Substitution
Laboratorieanalys Chemical structure
What Is HPMC?

Definition, Chemistry,
och Industrial Role

HPMC is produced by reacting purified cellulose with methyl chloride and propylene oxide under controlled alkaline conditions. This process introduces two types of substituent groups onto the cellulose backbone, each influencing the final product's performance profile in different ways.

Methoxyl Groups (–OCH₃)

Control solubility, thermal gelation behavior, and surface activity of the cellulose ether.

Hydroxypropoxyl Groups

Influence water retention capacity, viscosity development, and compatibility with other ingredients.

The combination and ratio of these two substituents — expressed as degree of methyl substitution (DS) and molar substitution of hydroxypropyl (MS) — determine the grade's performance profile. Viscosity, measured at 2% aqueous solution using Brookfield or Ubbelohde methods, is the most commonly referenced parameter for grade selection, ranging from below 100 mPa·s to above 200,000 mPa·s depending on the grade.

Why HPMC Is Widely Used

HPMC is non-ionic — compatible with a wide range of additives, surfactants, salts, and pH conditions. It is also biodegradable, odorless, tasteless, and free from animal-derived raw materials, making it suitable for regulated and sensitive applications from drymix mortar to pharmaceutical excipients and food systems.

Teknisk data

HPMC Technical
Referensdata

The following table provides a general technical reference for Hydroxypropyl Methyl Cellulose. Exact values vary by product grade, viscosity level, substitution type, particle size, surface treatment, and testing method. This information is intended as a formulation reference starting point, not a final product specification.

ArtikelTypisk referens
Produktens namnHydroxipropylmetylcellulosa
FörkortningHPMC
CAS-nummer9004-65-3
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UtseendeVitt till benvitt pulver
IontypIcke-jonisk
Molekylär grundCellulosaether (modifierad naturlig cellulosa)
RåvarukällaTräfiber eller bomullslinters
LöslighetSoluble in cold water; insoluble in hot water above gelation temperature; forms viscous solution
Termisk geleringGels upon heating; re-dissolves upon cooling (thermally reversible)
ViskositetsintervallMultiple grades: low / medium / high / extra-high viscosity
ViskositetsmätningTypically at 2% aqueous solution (Brookfield or Ubbelohde)
Surface TreatmentTreated (delayed hydration) or untreated options available
pH-stabilitetStable across approximately pH 3–11
Ionic CompatibilityCompatible with non-ionic, anionic, and many cationic systems
NyckelfunktionerThickening, water retention, film forming, binding, workability, stabilization
Application SystemsDrymix, liquid, semi-solid, pharmaceutical, food, industrial
Tillgängliga dokumentTDS, SDS, COA, produktrekommendation tillgänglig på begäran

Important: This table is a general reference only. For exact viscosity, pH, moisture content, ash content, particle size distribution, methoxyl content, hydroxypropoxyl content, and grade-specific values, please request the official TDS or COA from LANDERCOLL.

Betyg
Klassningsreferens

HPMC Product Grades —
Viscosity and Application Reference

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i.
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ii.
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iii.
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iv.
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v.
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Faster viscosity development — quick hydration, suitable for fast-dissolving and direct-hydration formulations.

Note: Viscosity ranges listed above are approximate references. Actual LANDERCOLL HPMC grades should be selected according to your formulation, testing method, application environment, and required documentation. Contact our team for specific grade recommendations.

Huvudfunktioner

Key Functions of
HPMC in Formulation

HPMC is a multifunctional cellulose ether. In most applications, it contributes more than one functional benefit simultaneously. Below is a structured overview of its primary functions across different system types.

Vattenretention
i.
Vattenretention

In cement-based and gypsum-based systems, HPMC forms a polymer network that physically restricts water migration. Higher viscosity grades and higher dosage levels provide stronger water retention — preventing rapid water loss, incomplete hydration, and surface cracking.

Förtjockning
ii.
Thickening & Viscosity Control

HPMC dissolves in cold water to form a viscous, pseudoplastic (shear-thinning) solution. Viscosity decreases under shear during mixing and recovers at rest — supporting both processability and in-place stability across drymix mortar, detergents, personal care, and coatings.

Användbarhet
iii.
Workability Improvement

In drymix construction materials, HPMC makes mortar smoother, more cohesive, and easier to spread, trowel, scrape, and finish. It is a combined result of water retention, viscosity building, and lubrication effects — particularly valued in tile adhesive, wall putty, and gypsum plaster.

iv.
Rheologikontroll

Supports flow control, sag resistance, leveling behavior, and application stability. Prevents mortar from sliding on vertical surfaces, contributes to controlled flow in self-leveling compounds, and maintains stable viscosity in coatings and detergents.

v.
Filmformation

HPMC forms a continuous, flexible film after water evaporation — used in pharmaceutical tablet coating, edible film systems, construction surface integrity, and selected water-based coatings as a binder component.

vi.
Binding, Cohesion & Suspension

Supports structural integrity in tablet manufacturing, green strength in ceramics, and cohesion in drymix mortar. Also helps maintain uniform suspension of pigments, fillers, mineral powders, and active ingredients in coatings, detergents, and pharmaceutical systems.

Användningsguide

HPMC Application
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HPMC grade selection should always start from the application. A grade optimized for tile adhesive will not necessarily perform well in a detergent, personal care, or pharmaceutical system. The table below provides a structured reference for common application-to-grade matching.

TillämpningRekommenderad klassriktningHuvudprestandakrav
Adhesiv för kakelplattorHigh to extra-high viscosityWater retention, open time, anti-slip, troweling feel
Väggspackel / Skim CoatMedium to high viscositySmooth scraping, water retention, surface finish
Cementputs / GipsMedium to high viscosityWorkability, spreadability, water retention
Gips PlasterMedium to high viscositySmooth application, water management, consistency
Självutjämnande massorLow to medium viscosityFlow control, stability, controlled water retention
EIFS / ETICS MortarHög viskositetOpen time, anti-sag, adhesion-related support
Vattentätt murbrukMedium to high viscosityWorkability, uniform coating, stable consistency
Murbruk för murverkMedium to high viscosityWater retention, workability, bond support
ReparationsbrukMedium to high viscosityAdhesion, workability, water retention
Flytande tvättmedelMedium viskositetTexture, viscosity, storage stability
Personlig vårdLow to medium viscositySmooth texture, viscosity control, stability
Pharmaceutical ApplicationsSuitable pharmaceutical gradeFilm coating, binding, controlled release, excipient
Food ApplicationsSuitable food grade (E464)Thickening, stabilization, texture control
KeramikMedium to high viscosityBinding, green strength, suspension
Vattenbaserade beläggningarLow to medium viscositycURL Too many subrequests by single Worker invocation. To configure this limit, refer to https://developers.cloudflare.com/workers/wrangler/configuration/#limits
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Dosering Guide

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efter Användning

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Mortar application dosage
TillämpningTypisk Referensdosering (% efter vikt)
Adhesiv för kakelplattor0.2% – 0.5%
Väggspackel / Skim Coat0.2% – 0.5%
Cementputs / Gips0.15% – 0.4%
Gips Plaster0.1% – 0.3%
Murbruk för murverk0.1% – 0.3%
Självutjämnande massorcURL Too many subrequests by single Worker invocation. To configure this limit, refer to https://developers.cloudflare.com/workers/wrangler/configuration/#limits
EIFS / ETICS Mortar0.2% – 0.5%
Vattentätt murbruk0.15% – 0.4%
Reparationsbruk0.15% – 0.4%
Flytande tvättmedel0.2% – 1.0%
Personlig vård0.1% – 1.0%
Vattenbaserade beläggningar0.1% – 0.8%
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Tillämpningar

Konstruktion &Drymix murbruk

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Adhesiv för kakelplattor

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  • Kakellim
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  • Cement render & plaster
  • Gipsgips
  • Självutjämnande föreningar
  • EIFS / ETICS-mörtel
  • Vattentätt murbruk
  • Murbruk
  • Reparationsmörtel
  • Isoleringsbruk
  • Joint fillers
  • Ready-mix dry mortar systems
Tillämpningar

Home Care & Personal Care Formuleringar

Home care detergents Hushållsprodukter & Rengöringsmedel

HPMC for Home Care
& Detergent Formulations

As a non-ionic polymer, HPMC is compatible with anionic and non-ionic surfactant systems commonly used in cleaning products. It builds smooth, stable viscosity that improves product appearance, pourability, and consumer perception — while helping maintain uniform suspension of insoluble components.

Typiska tillämpningar

Laundry liquid Dishwashing liquid Toilet bowl cleaner Surface cleaner Gel cleaner Multi-purpose cleaner
  • Kontrollerad viskositet och produktkropp
  • Stable texture and appearance over shelf life
  • Improved pourability and handling feel
  • Suspension support for insoluble components
  • Compatible with common surfactant systems
Personal care products Personlig vård

HPMC for Personal
Care Formulations

In personal care systems, HPMC functions as a viscosity modifier, texture enhancer, and formulation stabilizer. It is water-soluble, non-ionic, and free from animal-derived raw materials — making it suitable for a wide range of rinse-off and leave-on products where smooth, consistent texture and formulation stability across temperature and storage conditions are required.

Typiska tillämpningar

Shampoo & conditioner Body wash Ansiktsrengöring Hand soap Body lotion & cream Tandkräm Hair styling Intimate care
  • Smooth, uniform texture and sensory feel
  • Controlled viscosity across temperature ranges
  • Stable formulation structure over shelf life
  • Non-ionic — does not interfere with charged ingredients
Läkemedel

HPMC for Pharmaceutical Applications

Suitable pharmaceutical grades of HPMC — referred to as Hypromellose in pharmacopoeial standards — are widely used as functional excipients in solid dosage forms, film coatings, and controlled-release systems. HPMC is recognized in the USP/NF, Ph. Eur., and JP pharmacopoeias.

Only grades manufactured and tested to pharmacopoeial standards should be used. Grade selection is based on viscosity grade, substitution type, regulatory compliance, and documentation requirements.

Typiska tillämpningar

  • Tablet binder (wet granulation & direct compression)
  • Film coating for immediate-release tablets
  • Matrix former for controlled-release tablets
  • HPMC capsule shell material (vegetarian alternative)
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  • Ophthalmic solutions & artificial tear formulations
  • Topical and semi-solid pharmaceutical systems

Läkemedelsapplikationer kräver lämplig graderingsval, farmakopeisk efterlevnad och relevant dokumentation. Kontakta LANDERCOLL för att diskutera tillgänglighet av läkemedelsgrader.

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Typiska tillämpningar

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Industriella tillämpningar

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Vattenbaserade beläggningar

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Texturbeläggningar

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Construction Adhesives & Sealants

Binding, cohesion support, and process stability in adhesive and sealant formulations.

Ceramic Processing

Green body forming, extrusion, pressing — binding, green strength, and suspension support before firing.

Textile Printing Pastes

Viscosity control and rheology management in textile printing formulations.

Paper Coating & Sizing

Film formation, binding, and surface integrity in paper coating and sizing applications.

Specialty Industrial Fluids

Thickening, process control, and stability in specialty fluid formulations across various industrial sectors.

Agricultural Formulations

Viscosity building, suspension stability, and film formation in selected agricultural product systems.

Produktjämförelse

HPMC vs Other
Cellulosaetrar

Cellulose ethers are a family of water-soluble polymers, each with distinct chemical structures and performance profiles. LANDERCOLL supplies HPMC, HEMC/MHEC, HEC, and CMC — the four most widely used in industrial formulation. Understanding the differences helps formulators select the most appropriate product.

HPMC
Hydroxipropylmetylcellulosa
Icke-jonisk

Versatile water retention, thickening, film forming, workability, broad application compatibility.

Bygg · Pharma · Mat · Personlig vård · Rengöringsmedel · Industri
HEMC
Hydroxyethyl Methyl Cellulose (MHEC)
Icke-jonisk

Strong construction performance, excellent water retention, good anti-sag in drymix mortar.

Tile adhesive · Wall putty · Cement plaster · Gypsum · EIFS/ETICS
HEC
Hydroxietylcellulosa
Icke-jonisk

Excellent rheology control in aqueous systems, strong latex compatibility for coatings.

Water-based paints · Coatings · Cleaners · Personal care
CMC
Karboxymetylcellulosa
Anjonisk

Thickening, binding, stabilization, texture control; cost-effective across many systems.

Food · Detergents · Ceramics · Pharma · Oilfield · Paper

HPMC vs HEMC/MHEC for Construction

Both are non-ionic cellulose ethers for drymix construction materials and can deliver similar core functions. The choice depends on specific performance targets, regional market preferences, formulation system, and cost considerations. In many markets, HEMC/MHEC is preferred for high-performance tile adhesive and plaster due to its water retention profile. HPMC remains widely used globally across a broader range of industries.

HPMC vs HEC for Coatings

For water-based architectural coatings and latex paint systems, HEC is generally the preferred cellulose ether due to its strong compatibility with latex polymers and its well-established use in paint formulation. HPMC may be considered in specific coating systems, texture coatings, or where its film-forming or thermal gelation properties offer a formulation advantage.

Efter bransch

HPMC Grade Directions
Efter bransch

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Grade Direction · i.
Byggnadsklass

Designed for drymix construction materials requiring water retention, workability improvement, open time extension, anti-sag performance, and application consistency. Surface-treated grades commonly used.

Tile adhesive · Wall putty · Cement plaster · Gypsum plaster · Masonry mortar · Self-leveling · EIFS/ETICS · Waterproof mortar · Repair mortar · Insulation mortar
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Grade Direction · ii.
Tvättmedelsklass

Designed for home care and cleaning systems where viscosity building, texture stability, product body, and storage stability are important. Compatible with common anionic and non-ionic surfactant systems.

Laundry liquid · Dishwashing liquid · Toilet cleaner · Surface cleaner · Gel cleaner
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Grade Direction · iii.
Personvårdsklass

Designed for personal care products where smooth texture, stable viscosity, and user-friendly application feel are required. Non-ionic and compatible with a wide range of personal care actives.

Shampoo · Body wash · Facial cleanser · Lotion · Cream · Toothpaste · Styling products
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Grade Direction · iv.
Pharmaceutical Grade (Hypromellose)

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Logistik & Dokumentation

Förpackning, Förvaring & Tillgängliga dokument

Förpackning & Förvaring

Förpackning och Förvaring

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Standardförpackning

  • 25 kg per säck
  • Papperssäck med inre fuktspärrande polyetenliner
  • Pallad förpackning tillgänglig på begäran
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Förvaringsrekommendationer

  • Förvara på en sval, torr och välventilerad plats
  • Håll borta från fukt, direkt solljus och värmekällor
  • Håll förpackningen förseglad när den inte används
  • Undvik kontaminering under hantering och överföring
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  • Förvara inte nära starka oxidationsmedel eller reaktiva kemikalier
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Dokumentation

Produktdokumentation
Tillgänglig på begäran

LANDERCOLL kan tillhandahålla produktrelaterad dokumentation för att stödja formuleringsutvärdering, inköpsgranskning, teknisk kommunikation, regulatoriska inlämningar och interna godkännandeprocesser.

Tillgängliga dokument

  • Teknisk datablad (TDS)
  • Säkerhetsdatablad (SDS / MSDS)
  • Analyscertifikat (COA)
  • Produktbroschyr och tillämpningsguide
  • Klassificeringsrekommendationsdokument
  • Förpacknings- och lagringsspecifikation
  • Exportrelaterad dokumentation, där tillämpligt

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Begär produktdokument
Förfrågningsguide

Hur man begär
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i.
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iv.
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Destination country or target market. Documentation requirements (TDS, SDS, COA, food/pharma compliance documents). Timeline for evaluation or sourcing decision.

VANLIGA FRÅGOR

Vanliga frågor och svar
About HPMC

What is HPMC used for?

HPMC (CAS 9004-65-3) is used as a multifunctional cellulose ether additive across many industries. Its primary functions include water retention, thickening, workability improvement, film formation, binding, and formulation stabilization. Most widely used in drymix construction materials, and also in detergents, personal care, pharmaceutical excipients, food systems (E464), coatings, ceramics, and specialty industrial applications.

What does HPMC do in tile adhesive?

In tile adhesive, HPMC improves water retention to support cement hydration, extends open time to give installers more working time, provides anti-slip behavior to prevent tiles from sliding on vertical surfaces, and improves troweling feel and application consistency. High to extra-high viscosity grades are typically used, at dosages of 0.2%–0.5% of the dry mix weight.

What viscosity of HPMC is used for tile adhesive?

Tile adhesive commonly uses high to extra-high viscosity HPMC, typically in the range of 50,000–200,000 mPa·s (measured at 2% aqueous solution). The exact viscosity grade depends on the formulation type, tile size and weight, required open time, anti-slip performance target, and application conditions. Final grade selection should be confirmed through formulation testing.

What is the typical dosage of HPMC in tile adhesive?

The typical reference dosage for HPMC in tile adhesive is 0.2%–0.5% by weight of the dry mix. This range is widely referenced in the drymix mortar industry as a starting point. However, the optimal dosage depends on the specific formulation, cement type, filler quality, target open time, water retention requirement, and application conditions. Final dosage must be confirmed through laboratory and field testing.

What does HPMC do in wall putty?

In wall putty and skim coat, HPMC improves water retention to prevent rapid drying, enhances scraping smoothness and surface finish quality, improves spreading behavior and workability, and helps maintain consistent product texture during application. Medium to high viscosity grades are typically used at dosages of 0.2%–0.5%.

What is the difference between HPMC and HEMC?

HPMC uses hydroxypropyl groups while HEMC uses hydroxyethyl groups on the cellulose backbone, affecting water retention profile, dissolution behavior, and performance in specific applications. Both are used in tile adhesive, wall putty, and plaster. HPMC is more widely used across multiple industries including pharma, food, and personal care, while HEMC/MHEC is particularly established in European drymix construction markets.

Is HPMC the same as Hypromellose?

Yes. Hypromellose is the International Nonproprietary Name (INN) and pharmacopoeial name for HPMC. It is used in pharmaceutical and food regulatory contexts. HPMC and Hypromellose refer to the same chemical substance (CAS 9004-65-3).

Is HPMC a food additive?

Yes. HPMC is approved as a food additive under the code E464 in the European Union and is recognized in food regulations in many other markets. Food applications require suitable food-grade HPMC that meets applicable purity and safety standards, and compliance with the specific food regulations of the target market is required.

Is HPMC used in pharmaceuticals?

Yes. Suitable pharmaceutical grades — referred to as Hypromellose — are widely used as excipients in tablet manufacturing, film coating, controlled-release systems, HPMC capsule shells, and ophthalmic formulations. HPMC is listed in the USP/NF, Ph. Eur., and JP pharmacopoeias. Pharmaceutical applications require grades manufactured and tested to pharmacopoeial standards.

What is the difference between surface-treated and non-surface-treated HPMC?

Surface-treated HPMC delays hydration when it contacts water, preventing premature lump formation and allowing the powder to disperse evenly before viscosity develops — commonly preferred in drymix mortar systems. Non-surface-treated HPMC dissolves more quickly and is preferred in systems where fast viscosity development is required.

Hur väljer jag rätt HPMC-kvalitet?

The right HPMC grade depends on your application, required viscosity level, formulation system type (cement-based, gypsum-based, liquid, semi-solid), processing conditions, dissolution behavior requirement, and final performance targets. Contact LANDERCOLL with your application details, and our team can recommend suitable grade directions and support your formulation evaluation.

Can HPMC be used in multiple industries?

Yes. HPMC is one of the most versatile cellulose ethers, used across construction, home care, personal care, pharmaceuticals, food, coatings, ceramics, and specialty industrial sectors. Different industries require different grade selections — contact LANDERCOLL to identify the most suitable grade direction for your specific application and market.

Varför LANDERCOLL

Varför välja LANDERCOLL HPMC

i.

Fokuserad Expertis inom Cellulosaföreningar

LANDERCOLL focuses on cellulose ether products — HPMC, HEMC/MHEC, HEC, and CMC. This product focus allows us to develop deeper application knowledge and provide more relevant technical support compared to general chemical distributors.

ii.

Application-Oriented Grade Matching

We help customers select HPMC based on real performance requirements — water retention, viscosity level, workability, open time, texture, stability, and processing behavior — rather than simply offering a product catalog.

iii.

Brett branschomfång

LANDERCOLL HPMC supports customers in construction materials, detergents, personal care, pharmaceuticals, food, coatings, ceramics, and specialty industrial sectors across multiple global markets.

iv.

Teknisk dokumentationsstöd

We provide TDS, SDS, COA, product recommendation documents, and application guides to support your evaluation, purchasing review, and internal approval processes.

v.

Långsiktigt leveranspartnerskap

Vårt mål är att stödja kunder från initial produktförfrågan till formuleringsprovning, inköpsbeslut och långsiktigt leveranssamarbete — med konsekvent produktkvalitet och lyhörd kommunikation.

Kontakta oss

Find the Right HPMC Grade
för Din ansökan

LANDERCOLL HPMC supports manufacturers across construction materials, detergents, personal care, pharmaceuticals, food, coatings, ceramics, and specialty industrial applications. Whether you are developing a new formulation, optimizing an existing product, or evaluating a new cellulose ether supplier, our team can help you identify the most suitable grade and provide the documentation and technical support you need.

~ Din förfrågan · MMXXV ~
Produkt HPMC · CAS 9004-65-3
Tillämpning Din målformulering
Klassningsriktning Low · Medium · High · XH
Surface Treatment Treated or non-treated
Dokument TDS · SDS · COA
Marknad Land & segment
Industrier Construction · Pharma · Food · Care