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CAS 9004-65-3 · E464 EINECS 618-389-1

HPMC Hydroxypropylmetylcelulóza

Definition, Chemistry, and Industrial Role — a complete reference for formulators across construction, pharma, food, personal care, and industrial sectors.

HPMC is a water-soluble, non-ionic cellulose ether produced by chemically modifying natural cellulose derived from wood pulp or cotton linter. It delivers multiple functional benefits — water retention, thickening, film forming, binding, and workability improvement — within a single versatile ingredient.

~ Rýchly odkaz ~
Celé meno Hydroxypropylmetylcelulóza
Číslo CAS 9004-65-3
Food Code E464
Typ iónu Neiónové
Rozpustnosť Cold water soluble
Pharma Name Hypromellose
Vzhľad Biely až takmer biely prášok
Chémia
Cellulose ether chemistry lab
DS·MS Substitution
Laboratórna analýza Chemical structure
What Is HPMC?

Definition, Chemistry,
a Industrial Role

HPMC is produced by reacting purified cellulose with methyl chloride and propylene oxide under controlled alkaline conditions. This process introduces two types of substituent groups onto the cellulose backbone, each influencing the final product's performance profile in different ways.

Methoxyl Groups (–OCH₃)

Control solubility, thermal gelation behavior, and surface activity of the cellulose ether.

Hydroxypropoxyl Groups

Influence water retention capacity, viscosity development, and compatibility with other ingredients.

The combination and ratio of these two substituents — expressed as degree of methyl substitution (DS) and molar substitution of hydroxypropyl (MS) — determine the grade's performance profile. Viscosity, measured at 2% aqueous solution using Brookfield or Ubbelohde methods, is the most commonly referenced parameter for grade selection, ranging from below 100 mPa·s to above 200,000 mPa·s depending on the grade.

Why HPMC Is Widely Used

HPMC is non-ionic — compatible with a wide range of additives, surfactants, salts, and pH conditions. It is also biodegradable, odorless, tasteless, and free from animal-derived raw materials, making it suitable for regulated and sensitive applications from drymix mortar to pharmaceutical excipients and food systems.

Technické údaje

HPMC Technical
Referenčné údaje

The following table provides a general technical reference for Hydroxypropyl Methyl Cellulose. Exact values vary by product grade, viscosity level, substitution type, particle size, surface treatment, and testing method. This information is intended as a formulation reference starting point, not a final product specification.

PoložkaTypická referencia
Názov produktuHydroxypropylmetylcelulóza
SkratkaHPMC
Číslo CAS9004-65-3
Food Additive CodeE464
VzhľadBiely až takmer biely prášok
Typ iónuNeiónové
Molekulárny základCelulózový éter (modifikovaná prírodná celulóza)
Zdroj surovinyDrevo na vlákninu alebo bavlnené vlákna
RozpustnosťSoluble in cold water; insoluble in hot water above gelation temperature; forms viscous solution
Tepelná geláciaGels upon heating; re-dissolves upon cooling (thermally reversible)
Rozsah viskozityViaceré triedy: nízka / stredná / vysoká / extra vysoká viskozita
Meranie viskozityTypically at 2% aqueous solution (Brookfield or Ubbelohde)
Úprava povrchuTreated (delayed hydration) or untreated options available
Stabilita pHStable across approximately pH 3–11
Iónová kompatibilitaCompatible with non-ionic, anionic, and many cationic systems
Kľúčové funkcieThickening, water retention, film forming, binding, workability, stabilization
Application SystemsDrymix, liquid, semi-solid, pharmaceutical, food, industrial
Dostupné dokumentyTDS, SDS, COA, odporúčanie produktu na požiadanie

Important: This table is a general reference only. For exact viscosity, pH, moisture content, ash content, particle size distribution, methoxyl content, hydroxypropoxyl content, and grade-specific values, please request the official TDS or COA from LANDERCOLL.

Triedy
Referenčná trieda

HPMC Product Grades —
Referenčné hodnoty viskozity a použitia

LANDERCOLL HPMC is available in multiple grade directions based on viscosity level, surface treatment, dissolution behavior, and target application. The information below is designed as a product selection reference. Final grade selection should always be confirmed through formulation testing and direct technical discussion with our team.

i.
Low Viscosity HPMC
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ii.
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iii.
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iv.
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Hlavné funkcie

Key Functions of
HPMC in Formulation

HPMC is a multifunctional cellulose ether. In most applications, it contributes more than one functional benefit simultaneously. Below is a structured overview of its primary functions across different system types.

Zadržiavanie vody
i.
Zadržiavanie vody

In cement-based and gypsum-based systems, HPMC forms a polymer network that physically restricts water migration. Higher viscosity grades and higher dosage levels provide stronger water retention — preventing rapid water loss, incomplete hydration, and surface cracking.

Zahusťovanie
ii.
Thickening & Viscosity Control

HPMC dissolves in cold water to form a viscous, pseudoplastic (shear-thinning) solution. Viscosity decreases under shear during mixing and recovers at rest — supporting both processability and in-place stability across drymix mortar, detergents, personal care, and coatings.

Spracovateľnosť
iii.
Workability Improvement

In drymix construction materials, HPMC makes mortar smoother, more cohesive, and easier to spread, trowel, scrape, and finish. It is a combined result of water retention, viscosity building, and lubrication effects — particularly valued in tile adhesive, wall putty, and gypsum plaster.

iv.
Riadenie reológie

Supports flow control, sag resistance, leveling behavior, and application stability. Prevents mortar from sliding on vertical surfaces, contributes to controlled flow in self-leveling compounds, and maintains stable viscosity in coatings and detergents.

v.
Tvorba filmu

HPMC forms a continuous, flexible film after water evaporation — used in pharmaceutical tablet coating, edible film systems, construction surface integrity, and selected water-based coatings as a binder component.

vi.
Binding, Cohesion & Suspension

Supports structural integrity in tablet manufacturing, green strength in ceramics, and cohesion in drymix mortar. Also helps maintain uniform suspension of pigments, fillers, mineral powders, and active ingredients in coatings, detergents, and pharmaceutical systems.

Príručka aplikácie

HPMC Application
Selection Guide

HPMC grade selection should always start from the application. A grade optimized for tile adhesive will not necessarily perform well in a detergent, personal care, or pharmaceutical system. The table below provides a structured reference for common application-to-grade matching.

AplikáciaOdporúčané smerovanie triedyHlavné požiadavky na výkon
Lepidlo na dlaždiceHigh to extra-high viscosityWater retention, open time, anti-slip, troweling feel
Tmel na steny / Skim CoatStredná až vysoká viskozitaSmooth scraping, water retention, surface finish
Cementová omietka / omietkaStredná až vysoká viskozitaWorkability, spreadability, water retention
SadraStredná až vysoká viskozitaSmooth application, water management, consistency
Samonivelačné zmesiNízka až stredná viskozitaFlow control, stability, controlled water retention
EIFS / ETICS MortarVysoká viskozitaOpen time, anti-sag, adhesion-related support
Vodotesná maltaStredná až vysoká viskozitaWorkability, uniform coating, stable consistency
Murovacia maltaStredná až vysoká viskozitaWater retention, workability, bond support
Opravná maltaStredná až vysoká viskozitaAdhesion, workability, water retention
Tekutý čistiaci prostriedokStredná viskozitaTexture, viscosity, storage stability
Osobná starostlivosťNízka až stredná viskozitaSmooth texture, viscosity control, stability
Pharmaceutical ApplicationsSuitable pharmaceutical gradeFilm coating, binding, controlled release, excipient
Food ApplicationsSuitable food grade (E464)Thickening, stabilization, texture control
KeramikaStredná až vysoká viskozitaBinding, green strength, suspension
Vodou riediteľné náteryNízka až stredná viskozitaThickening, film formation, particle suspension
Industrial AdhesivesStredná až vysoká viskozitaBinding, cohesion, process stability

Grade direction is a starting reference. Final selection should be confirmed through laboratory testing under your specific formulation conditions, water quality, temperature range, and application method.

Sprievodca dávkovaním

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Mortar application dosage
AplikáciaTypical Reference Dosage (% by weight)
Lepidlo na dlaždicecURL Too many subrequests by single Worker invocation. To configure this limit, refer to https://developers.cloudflare.com/workers/wrangler/configuration/#limits
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Cementová omietka / omietka0.15% – 0.4%
Sadra0.1% – 0.3%
Murovacia malta0.1% – 0.3%
Samonivelačné zmesicURL Too many subrequests by single Worker invocation. To configure this limit, refer to https://developers.cloudflare.com/workers/wrangler/configuration/#limits
EIFS / ETICS MortarcURL Too many subrequests by single Worker invocation. To configure this limit, refer to https://developers.cloudflare.com/workers/wrangler/configuration/#limits
Vodotesná malta0.15% – 0.4%
Opravná malta0.15% – 0.4%
Tekutý čistiaci prostriedok0.2% – 1.0%
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Aplikácie

Výstavba &Suchá maltová zmes

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Lepidlo na dlaždice

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  • Lepidlo na dlaždice
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  • Sadra
  • Samonivelačné zmesi
  • Omietka EIFS / ETICS
  • Vodotesná malta
  • Murárska malta
  • Opravná malta
  • Izolačná malta
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Aplikácie

cURL Too many subrequests by single Worker invocation. To configure this limit, refer to https://developers.cloudflare.com/workers/wrangler/configuration/#limits Formulácie

Home care detergents Domáca starostlivosť a čistiace prostriedky

HPMC for Home Care
& Detergent Formulations

As a non-ionic polymer, HPMC is compatible with anionic and non-ionic surfactant systems commonly used in cleaning products. It builds smooth, stable viscosity that improves product appearance, pourability, and consumer perception — while helping maintain uniform suspension of insoluble components.

Typické aplikácie

Laundry liquid Prostriedok na umývanie riadu Čistiaci prostriedok na toalety Surface cleaner Gélový čistič Univerzálny čistič
  • Controlled viscosity and product body
  • Stable texture and appearance over shelf life
  • Improved pourability and handling feel
  • Suspension support for insoluble components
  • Compatible with common surfactant systems
Personal care products Osobná starostlivosť

HPMC for Personal
Vzorce pre starostlivosť

In personal care systems, HPMC functions as a viscosity modifier, texture enhancer, and formulation stabilizer. It is water-soluble, non-ionic, and free from animal-derived raw materials — making it suitable for a wide range of rinse-off and leave-on products where smooth, consistent texture and formulation stability across temperature and storage conditions are required.

Typické aplikácie

Šampón a kondicionér Sprchový gél Pleťový čistiaci prostriedok Ručný mydlo Telové mlieko a krém Zubná pasta Hair styling Intímna starostlivosť
  • Smooth, uniform texture and sensory feel
  • Controlled viscosity across temperature ranges
  • Stable formulation structure over shelf life
  • Non-ionic — does not interfere with charged ingredients
Farmaceutické

HPMC for Pharmaceutical Applications

Suitable pharmaceutical grades of HPMC — referred to as Hypromellose in pharmacopoeial standards — are widely used as functional excipients in solid dosage forms, film coatings, and controlled-release systems. HPMC is recognized in the USP/NF, Ph. Eur., and JP pharmacopoeias.

Only grades manufactured and tested to pharmacopoeial standards should be used. Grade selection is based on viscosity grade, substitution type, regulatory compliance, and documentation requirements.

Typické aplikácie

  • Tablet binder (wet granulation & direct compression)
  • Film coating for immediate-release tablets
  • Matrix former for controlled-release tablets
  • HPMC capsule shell material (vegetarian alternative)
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  • Ophthalmic solutions & artificial tear formulations
  • Topical and semi-solid pharmaceutical systems

Pharmaceutical applications require suitable grade selection, pharmacopoeial compliance, and relevant documentation. Contact LANDERCOLL to discuss pharmaceutical grade availability.

Discuss Pharma Grades
Food · E464

HPMC for Food Applications (E464)

Hydroxypropyl Methyl Cellulose is approved as a food additive under E464 in the European Union and is recognized in food regulations in many other markets. Suitable food-grade HPMC may be used as a thickener, stabilizer, emulsifier, film former, and texture modifier.

Food applications require HPMC grades meeting relevant food safety standards including purity specifications, heavy metal limits, and microbiological requirements. Compliance with the specific food regulations of the target market is required.

Typické aplikácie

  • Bakery products including gluten-free formulations
  • Sauces, dressings, and condiments
  • Frozen food systems (ice cream, frozen desserts)
  • Beverage systems
  • Edible film and coating applications
  • Vegetarian & vegan food products (gelatin alternative)
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Industrial coatings application
Vodou riediteľné nátery

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Textúrové nátery

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Viscosity building, suspension stability, and film formation in selected agricultural product systems.

Porovnanie produktov

HPMC vs Other
Etery celulózy

Cellulose ethers are a family of water-soluble polymers, each with distinct chemical structures and performance profiles. LANDERCOLL supplies HPMC, HEMC/MHEC, HEC, and CMC — the four most widely used in industrial formulation. Understanding the differences helps formulators select the most appropriate product.

HPMC
Hydroxypropylmetylcelulóza
Neiónové

Versatile water retention, thickening, film forming, workability, broad application compatibility.

Construction · Pharma · Food · Personal care · Detergents · Industrial
HEMC
Hydroxyethyl Methyl Cellulose (MHEC)
Neiónové

Strong construction performance, excellent water retention, good anti-sag in drymix mortar.

Tile adhesive · Wall putty · Cement plaster · Gypsum · EIFS/ETICS
HEC
Hydroxyetylcelulóza
Neiónové

Excellent rheology control in aqueous systems, strong latex compatibility for coatings.

Water-based paints · Coatings · Cleaners · Personal care
CMC
Karboxymetylcelulóza
Aniónové

Thickening, binding, stabilization, texture control; cost-effective across many systems.

Potraviny · Čistiace prostriedky · Keramika · Farmaceutický priemysel · Ropné polia · Papier

HPMC vs HEMC/MHEC for Construction

Both are non-ionic cellulose ethers for drymix construction materials and can deliver similar core functions. The choice depends on specific performance targets, regional market preferences, formulation system, and cost considerations. In many markets, HEMC/MHEC is preferred for high-performance tile adhesive and plaster due to its water retention profile. HPMC remains widely used globally across a broader range of industries.

HPMC vs HEC for Coatings

For water-based architectural coatings and latex paint systems, HEC is generally the preferred cellulose ether due to its strong compatibility with latex polymers and its well-established use in paint formulation. HPMC may be considered in specific coating systems, texture coatings, or where its film-forming or thermal gelation properties offer a formulation advantage.

Podľa odvetvia

HPMC Grade Directions
podľa odvetvia

Stavebná kvalita
Smernica triedy · i.
Stavebná trieda

Designed for drymix construction materials requiring water retention, workability improvement, open time extension, anti-sag performance, and application consistency. Surface-treated grades commonly used.

Tile adhesive · Wall putty · Cement plaster · Gypsum plaster · Masonry mortar · Self-leveling · EIFS/ETICS · Waterproof mortar · Repair mortar · Insulation mortar
Kvalita čistiacich prostriedkov
Smernica triedy · ii.
Trieda na čistiace prostriedky

Designed for home care and cleaning systems where viscosity building, texture stability, product body, and storage stability are important. Compatible with common anionic and non-ionic surfactant systems.

Laundry liquid · Dishwashing liquid · Toilet cleaner · Surface cleaner · Gel cleaner
Kvalita osobnej starostlivosti
Smerovanie stupňa · iii.
Trieda osobnej starostlivosti

Designed for personal care products where smooth texture, stable viscosity, and user-friendly application feel are required. Non-ionic and compatible with a wide range of personal care actives.

Shampoo · Body wash · Facial cleanser · Lotion · Cream · Toothpaste · Styling products
Pharmaceutical grade
Smerovanie stupňa · iv.
Pharmaceutical Grade (Hypromellose)

Manufactured and tested to pharmacopoeial standards (USP/NF, Ph. Eur., JP). For pharmaceutical excipient applications where binding, coating, controlled release, or film performance may be required.

Tablet binder · Film coating · Controlled-release matrix · HPMC capsule shells · Oral film systems · Ophthalmic applications
Food grade E464
Smerovanie stupňa · v.
Food Grade (E464)

Compliant with applicable food additive regulations. Designed for food systems where texture control, water management, stabilization, and formulation consistency are required.

Bakery products · Sauces & dressings · Frozen food · Edible films · Texture-modified food · Vegan & halal applications
Priemyselná kvalita
Smerovanie stupňa · vi.
Priemyselná trieda

Designed for specialty industrial systems requiring thickening, binding, suspension stability, and process control across various non-food, non-pharma applications.

Ceramics processing · Construction adhesives · Textile printing · Paper-related systems · Specialty industrial fluids
Logistika a dokumentácia

Balenie, skladovanie a Dostupné dokumenty

Balenie a skladovanie

Balenie a skladovanie

LANDERCOLL HPMC is supplied in industrial packaging suitable for transportation, storage, and production handling. Cellulose ether powders are hygroscopic — proper storage conditions help maintain powder flowability, dissolution performance, and application effectiveness throughout product shelf life.

Štandardné balenie

  • 25 kg na vrece
  • Papierové vrece s vnútornou ochrannou polyetylénovou vrstvou proti vlhkosti
  • Paletizované balenie dostupné na požiadanie
  • Customized packaging options can be discussed for long-term supply cooperation

Odporúčania pre skladovanie

  • Skladujte na chladnom, suchom a dobre vetranom prostredí
  • Uchovávajte mimo vlhkosti, priameho slnečného žiarenia a zdrojov tepla
  • Udržiavajte balenie uzavreté, keď sa nepoužíva
  • Vyhýbajte sa kontaminácii počas manipulácie a prepravy
  • Use within the recommended shelf life stated in product documentation
  • Neukladajte v blízkosti silných oxidačných činidiel alebo reaktívnych chemikálií
Industrial packaging warehouse
Dokumentácia

Dokumentácia produktu
Dostupné na požiadanie

LANDERCOLL môže poskytnúť dokumentáciu súvisiacu s produktom na podporu hodnotenia formulácie, kontrolu nákupu, technickú komunikáciu, regulačné podanie a interné schvaľovacie procesy.

Dostupné dokumenty

  • Technický list (TDS)
  • Bezpečnostný list (SDS / MSDS)
  • Certifikát o analýze (COA)
  • Brožúra produktu a sprievodca aplikáciou
  • Odporúčací dokument o triede
  • Špecifikácia balenia a skladovania
  • Dokumentácia súvisiaca s exportom, kde je to vhodné

All documentation is provided to help customers complete their internal evaluation, purchasing approval, and regulatory review processes efficiently. Contact our team to request specific documents for your application or market requirements.

Požiadať o produktové dokumenty
Sprievodca dopytom

Ako požiadať o
Right HPMC Grade

To help our team recommend the most suitable HPMC grade for your application, please include as much of the following information as possible when contacting us. A detailed inquiry allows us to provide a more accurate grade recommendation and support your evaluation more efficiently.

i.
Application & Formulation System

Product application (e.g., tile adhesive, wall putty, shampoo, tablet coating) and formulation system type (cement-based, gypsum-based, liquid, semi-solid, other).

ii.
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iii.
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ČASTO KLADENÉ OTÁZKY

Často kladené otázky
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Yes. HPMC is approved as a food additive under the code E464 in the European Union and is recognized in food regulations in many other markets. Food applications require suitable food-grade HPMC that meets applicable purity and safety standards, and compliance with the specific food regulations of the target market is required.

Is HPMC used in pharmaceuticals?

Yes. Suitable pharmaceutical grades — referred to as Hypromellose — are widely used as excipients in tablet manufacturing, film coating, controlled-release systems, HPMC capsule shells, and ophthalmic formulations. HPMC is listed in the USP/NF, Ph. Eur., and JP pharmacopoeias. Pharmaceutical applications require grades manufactured and tested to pharmacopoeial standards.

What is the difference between surface-treated and non-surface-treated HPMC?

Surface-treated HPMC delays hydration when it contacts water, preventing premature lump formation and allowing the powder to disperse evenly before viscosity develops — commonly preferred in drymix mortar systems. Non-surface-treated HPMC dissolves more quickly and is preferred in systems where fast viscosity development is required.

Ako si vybrať správnu triedu HPMC?

The right HPMC grade depends on your application, required viscosity level, formulation system type (cement-based, gypsum-based, liquid, semi-solid), processing conditions, dissolution behavior requirement, and final performance targets. Contact LANDERCOLL with your application details, and our team can recommend suitable grade directions and support your formulation evaluation.

Can HPMC be used in multiple industries?

Yes. HPMC is one of the most versatile cellulose ethers, used across construction, home care, personal care, pharmaceuticals, food, coatings, ceramics, and specialty industrial sectors. Different industries require different grade selections — contact LANDERCOLL to identify the most suitable grade direction for your specific application and market.

Prečo LANDERCOLL

Prečo si vybrať LANDERCOLL HPMC

i.

Zameranie na špecializáciu v oblasti celulózových éterov

LANDERCOLL focuses on cellulose ether products — HPMC, HEMC/MHEC, HEC, and CMC. This product focus allows us to develop deeper application knowledge and provide more relevant technical support compared to general chemical distributors.

ii.

Application-Oriented Grade Matching

We help customers select HPMC based on real performance requirements — water retention, viscosity level, workability, open time, texture, stability, and processing behavior — rather than simply offering a product catalog.

iii.

Široké pokrytie odvetví

LANDERCOLL HPMC supports customers in construction materials, detergents, personal care, pharmaceuticals, food, coatings, ceramics, and specialty industrial sectors across multiple global markets.

iv.

Podpora technickej dokumentácie

We provide TDS, SDS, COA, product recommendation documents, and application guides to support your evaluation, purchasing review, and internal approval processes.

v.

Dlhodobé partnerstvo v dodávkach

Naším cieľom je podporovať zákazníkov od počiatočného dopytu po výrobok cez testovanie formulácie, rozhodnutia o zdrojoch a dlhodobú spoluprácu v dodávkach — s konzistentnou kvalitou produktu a rýchlou komunikáciou.

Kontaktujte nás

Find the Right HPMC Grade
pre Vaša žiadosť

LANDERCOLL HPMC supports manufacturers across construction materials, detergents, personal care, pharmaceuticals, food, coatings, ceramics, and specialty industrial applications. Whether you are developing a new formulation, optimizing an existing product, or evaluating a new cellulose ether supplier, our team can help you identify the most suitable grade and provide the documentation and technical support you need.

~ Vaša žiadosť · MMXXV ~
Produkt HPMC · CAS 9004-65-3
Aplikácia Vaša cieľová formulácia
Smerovanie triedy Nízka · Stredná · Vysoká · XH
Úprava povrchu Treated or non-treated
Dokumenty TDS · SDS · COA
Trh Krajina a segment
Odvetvia Construction · Pharma · Food · Care