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CAS 9004-65-3 · E464 EINECS 618-389-1

HPMC Гидроксипропилметилцеллюлоза

Definition, Chemistry, and Industrial Role — a complete reference for formulators across construction, pharma, food, personal care, and industrial sectors.

HPMC is a water-soluble, non-ionic cellulose ether produced by chemically modifying natural cellulose derived from wood pulp or cotton linter. It delivers multiple functional benefits — water retention, thickening, film forming, binding, and workability improvement — within a single versatile ingredient.

~ Бысткое руководство ~
Полное имя Гидроксипропилметилцеллюлоза
CAS No. 9004-65-3
Food Code E464
Ionic Type Неионогенные
Растворимость Cold water soluble
Pharma Name Hypromellose
Внешний вид Порошок от белого до светло-белого цвета
Химия
Cellulose ether chemistry lab
DS·MS Substitution
Lab analysis Chemical structure
What Is HPMC?

Definition, Chemistry,
и Industrial Role

HPMC is produced by reacting purified cellulose with methyl chloride and propylene oxide under controlled alkaline conditions. This process introduces two types of substituent groups onto the cellulose backbone, each influencing the final product's performance profile in different ways.

Methoxyl Groups (–OCH₃)

Control solubility, thermal gelation behavior, and surface activity of the cellulose ether.

Hydroxypropoxyl Groups

Influence water retention capacity, viscosity development, and compatibility with other ingredients.

The combination and ratio of these two substituents — expressed as degree of methyl substitution (DS) and molar substitution of hydroxypropyl (MS) — determine the grade's performance profile. Viscosity, measured at 2% aqueous solution using Brookfield or Ubbelohde methods, is the most commonly referenced parameter for grade selection, ranging from below 100 mPa·s to above 200,000 mPa·s depending on the grade.

Why HPMC Is Widely Used

HPMC is non-ionic — compatible with a wide range of additives, surfactants, salts, and pH conditions. It is also biodegradable, odorless, tasteless, and free from animal-derived raw materials, making it suitable for regulated and sensitive applications from drymix mortar to pharmaceutical excipients and food systems.

Технические данные

HPMC Technical
Reference Data

The following table provides a general technical reference for Hydroxypropyl Methyl Cellulose. Exact values vary by product grade, viscosity level, substitution type, particle size, surface treatment, and testing method. This information is intended as a formulation reference starting point, not a final product specification.

ItemTypical Reference
Название продуктаГидроксипропилметилцеллюлоза
AbbreviationHPMC
CAS No.9004-65-3
Food Additive CodeE464
Внешний видПорошок от белого до светло-белого цвета
Ionic TypeНеионогенные
Molecular BasisCellulose ether (modified natural cellulose)
Raw Material SourceWood pulp or cotton linter
РастворимостьSoluble in cold water; insoluble in hot water above gelation temperature; forms viscous solution
Термическая гелеобразованиеGels upon heating; re-dissolves upon cooling (thermally reversible)
Viscosity RangecURL Too many subrequests by single Worker invocation. To configure this limit, refer to https://developers.cloudflare.com/workers/wrangler/configuration/#limits
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Стабильность pHcURL Too many subrequests by single Worker invocation. To configure this limit, refer to https://developers.cloudflare.com/workers/wrangler/configuration/#limits
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Классы
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i.
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ii.
Medium Viscosity HPMC
Typically 5,000–50,000 mPa·s
Wall putty, skim coat, detergent, personal care, general industrial systems.
Texture · Viscosity building · Smooth workability
iii.
High Viscosity HPMC
Typically 50,000–150,000 mPa·s
Tile adhesive, cement plaster, gypsum plaster, drymix mortar systems.
Water retention · Open time · Workability
iv.
Extra High Viscosity HPMC
Typically above 150,000 mPa·s
High-performance tile adhesive, thick-layer mortar, vertical application systems.
Strong water retention · Anti-sag · Extended open time
v.
Grades by Surface Treatment
Treated or non-treated options
Surface-Treated

Delayed hydration — easier dispersion, reduced lumping, controlled dissolution. Preferred for drymix systems.

Non-Surface-Treated

Faster viscosity development — quick hydration, suitable for fast-dissolving and direct-hydration formulations.

Note: Viscosity ranges listed above are approximate references. Actual LANDERCOLL HPMC grades should be selected according to your formulation, testing method, application environment, and required documentation. Contact our team for specific grade recommendations.

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Key Functions of
HPMC in Formulation

HPMC is a multifunctional cellulose ether. In most applications, it contributes more than one functional benefit simultaneously. Below is a structured overview of its primary functions across different system types.

Удержание воды
i.
Удержание воды

In cement-based and gypsum-based systems, HPMC forms a polymer network that physically restricts water migration. Higher viscosity grades and higher dosage levels provide stronger water retention — preventing rapid water loss, incomplete hydration, and surface cracking.

Сгущение
ii.
Thickening & Viscosity Control

HPMC dissolves in cold water to form a viscous, pseudoplastic (shear-thinning) solution. Viscosity decreases under shear during mixing and recovers at rest — supporting both processability and in-place stability across drymix mortar, detergents, personal care, and coatings.

Работоспособность
iii.
Улучшение удобства нанесения

In drymix construction materials, HPMC makes mortar smoother, more cohesive, and easier to spread, trowel, scrape, and finish. It is a combined result of water retention, viscosity building, and lubrication effects — particularly valued in tile adhesive, wall putty, and gypsum plaster.

iv.
Контроль реологии

Supports flow control, sag resistance, leveling behavior, and application stability. Prevents mortar from sliding on vertical surfaces, contributes to controlled flow in self-leveling compounds, and maintains stable viscosity in coatings and detergents.

v.
Формирование фильма

HPMC forms a continuous, flexible film after water evaporation — used in pharmaceutical tablet coating, edible film systems, construction surface integrity, and selected water-based coatings as a binder component.

vi.
Binding, Cohesion & Suspension

Supports structural integrity in tablet manufacturing, green strength in ceramics, and cohesion in drymix mortar. Also helps maintain uniform suspension of pigments, fillers, mineral powders, and active ingredients in coatings, detergents, and pharmaceutical systems.

Руководство по применению

HPMC Application
Руководство по выбору

HPMC grade selection should always start from the application. A grade optimized for tile adhesive will not necessarily perform well in a detergent, personal care, or pharmaceutical system. The table below provides a structured reference for common application-to-grade matching.

ПриложениеRecommended Grade DirectionОсновные требования к характеристикам
Клей для плиткиHigh to extra-high viscosityWater retention, open time, anti-slip, troweling feel
Шпаклевка для стен / грунтовкаMedium to high viscositySmooth scraping, water retention, surface finish
Цементная штукатуркаMedium to high viscosityРаботоспособность, распределяемость, удержание воды
Гипсовая штукатуркаMedium to high viscosityГладкое нанесение, управление водой, консистенция
Самовыравнивающиеся составыLow to medium viscositycURL Too many subrequests by single Worker invocation. To configure this limit, refer to https://developers.cloudflare.com/workers/wrangler/configuration/#limits
Морозостойкая штукатурка / ETICScURL Too many subrequests by single Worker invocation. To configure this limit, refer to https://developers.cloudflare.com/workers/wrangler/configuration/#limitscURL Too many subrequests by single Worker invocation. To configure this limit, refer to https://developers.cloudflare.com/workers/wrangler/configuration/#limits
Водостойкий растворMedium to high viscositycURL Too many subrequests by single Worker invocation. To configure this limit, refer to https://developers.cloudflare.com/workers/wrangler/configuration/#limits
Кладочный растворMedium to high viscositycURL Too many subrequests by single Worker invocation. To configure this limit, refer to https://developers.cloudflare.com/workers/wrangler/configuration/#limits
Ремонтная штукатуркаMedium to high viscositycURL Too many subrequests by single Worker invocation. To configure this limit, refer to https://developers.cloudflare.com/workers/wrangler/configuration/#limits
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Личный уходLow to medium viscositycURL Too many subrequests by single Worker invocation. To configure this limit, refer to https://developers.cloudflare.com/workers/wrangler/configuration/#limits
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КерамикаMedium to high viscositycURL Too many subrequests by single Worker invocation. To configure this limit, refer to https://developers.cloudflare.com/workers/wrangler/configuration/#limits
Водные покрытияLow to medium viscositycURL Too many subrequests by single Worker invocation. To configure this limit, refer to https://developers.cloudflare.com/workers/wrangler/configuration/#limits
cURL Too many subrequests by single Worker invocation. To configure this limit, refer to https://developers.cloudflare.com/workers/wrangler/configuration/#limitsMedium to high viscositycURL Too many subrequests by single Worker invocation. To configure this limit, refer to https://developers.cloudflare.com/workers/wrangler/configuration/#limits

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HPMC dosage depends on formulation design, raw material quality, target performance, ambient temperature, water quality, substrate type, and production process. The following ranges are general starting points for laboratory evaluation — not fixed usage standards.

For tile adhesive: 0.2%–0.5% is a widely referenced industry starting range. However, final dosage must be confirmed through laboratory testing and on-site performance evaluation, as substrate porosity, tile size, ambient temperature, and cement type all affect the optimal dosage.

Mortar application dosage
ПриложениеTypical Reference Dosage (% by weight)
Клей для плитки0.2% – 0.5%
Шпаклевка для стен / грунтовка0.2% – 0.5%
Цементная штукатурка0.15% – 0.4%
Гипсовая штукатурка0.1% – 0.3%
Кладочный раствор0.1% – 0.3%
Самовыравнивающиеся составы0.05% – 0.2%
Морозостойкая штукатурка / ETICS0.2% – 0.5%
Водостойкий раствор0.15% – 0.4%
Ремонтная штукатурка0.15% – 0.4%
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Личный уход0.1% – 1.0%
Водные покрытия0.1% – 0.8%
Food / Pharma / SpecialtyDepends on grade, regulation, and formulation design

These dosage ranges are general starting points. Adjust based on testing results under your specific formulation, raw materials, and application conditions.

Приложения

Строительство &Раствор Drymix

Construction is the largest and most established application area for HPMC globally — a critical additive for water retention, workability, open time, and anti-sag performance.

In drymix mortar systems, HPMC functions simultaneously as a water-retaining agent, rheology modifier, and workability enhancer. Without HPMC, cement-based and gypsum-based mortars tend to lose water too quickly to the substrate, resulting in poor hydration, weak bond strength, surface cracking, and difficult application.

Клей для плитки

Water retention, open time extension, anti-slip behavior, and troweling feel. High to extra-high viscosity grades, 0.2%–0.5% dosage. Surface-treated grades commonly preferred.

Шпаклевка для стен и тонкий слой

Scraping smoothness, water retention, surface finish quality. Medium to high viscosity, 0.2%–0.5% dosage.

Gypsum-Based Products

Controlled water retention without over-retarding set time. Smooth spreading, consistent texture, reduced surface defects. Medium to high viscosity grades.

Other Mortar Systems

Cement render, masonry mortar, self-leveling compounds, EIFS/ETICS, waterproof mortar, repair mortar, insulation mortar, joint fillers.

All Construction Applications
  • Плиточный клей
  • Шпатлевка и тонкий слой
  • Cement render & plaster
  • Гипсовая штукатурка
  • Самовыравнивающиеся составы
  • Раствор для систем внешних теплоизоляционных облицовочных систем / ETICS
  • Водонепроницаемый раствор
  • Кладочный раствор
  • Ремонтный раствор
  • Изоляционный раствор
  • Joint fillers
  • Ready-mix dry mortar systems
Приложения

Home Care & Personal Care Формулы

Home care detergents Домашний уход и моющие средства

HPMC for Home Care
& Detergent Formulations

As a non-ionic polymer, HPMC is compatible with anionic and non-ionic surfactant systems commonly used in cleaning products. It builds smooth, stable viscosity that improves product appearance, pourability, and consumer perception — while helping maintain uniform suspension of insoluble components.

Типичные применения

Laundry liquid Dishwashing liquid Toilet bowl cleaner Surface cleaner Gel cleaner Multi-purpose cleaner
  • Controlled viscosity and product body
  • Stable texture and appearance over shelf life
  • Improved pourability and handling feel
  • Suspension support for insoluble components
  • Compatible with common surfactant systems
Personal care products Личный уход

HPMC for Personal
Care Formulations

In personal care systems, HPMC functions as a viscosity modifier, texture enhancer, and formulation stabilizer. It is water-soluble, non-ionic, and free from animal-derived raw materials — making it suitable for a wide range of rinse-off and leave-on products where smooth, consistent texture and formulation stability across temperature and storage conditions are required.

Типичные применения

Shampoo & conditioner Гель для душа Очищающее средство для лица Hand soap cURL Too many subrequests by single Worker invocation. To configure this limit, refer to https://developers.cloudflare.com/workers/wrangler/configuration/#limits Зубная паста cURL Too many subrequests by single Worker invocation. To configure this limit, refer to https://developers.cloudflare.com/workers/wrangler/configuration/#limits cURL Too many subrequests by single Worker invocation. To configure this limit, refer to https://developers.cloudflare.com/workers/wrangler/configuration/#limits
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Фармацевтика

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Типичные применения

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Типичные применения

  • Bakery products including gluten-free formulations
  • Sauces, dressings, and condiments
  • Frozen food systems (ice cream, frozen desserts)
  • Beverage systems
  • Edible film and coating applications
  • Vegetarian & vegan food products (gelatin alternative)
  • Thermal gelation: gels when heated, re-dissolves when cooled
  • Improved freeze-thaw stability
  • Suitable for vegetarian, vegan, and halal-compliant formulations

Food applications require suitable grade selection and compliance with applicable food regulations in the target market.

Discuss Food Grades
Coatings & Industrial

HPMC for Coatings and
Промышленные применения

HPMC can be used in selected water-based coatings and specialty industrial systems where thickening, film formation, binding, suspension control, and process stability are required. In architectural coatings, HEC is more commonly used as the primary cellulose ether thickener; however, HPMC can be suitable in specific coating formulations and industrial systems.

Key performance benefits include viscosity control and thickening, film formation and surface integrity, binding and cohesion in ceramic and industrial systems, suspension stability for pigments and fillers, and process consistency in extrusion and forming operations.

Industrial coatings application
Водные покрытия

Selected architectural and decorative systems where HPMC's film-forming or thermal gelation properties offer a formulation advantage.

Текстурные покрытия

Decorative and texture coatings requiring stable viscosity, film formation, and consistent application behavior.

Construction Adhesives & Sealants

Binding, cohesion support, and process stability in adhesive and sealant formulations.

Ceramic Processing

Green body forming, extrusion, pressing — binding, green strength, and suspension support before firing.

Textile Printing Pastes

Viscosity control and rheology management in textile printing formulations.

Paper Coating & Sizing

Film formation, binding, and surface integrity in paper coating and sizing applications.

Specialty Industrial Fluids

Thickening, process control, and stability in specialty fluid formulations across various industrial sectors.

Agricultural Formulations

Viscosity building, suspension stability, and film formation in selected agricultural product systems.

Сравнение продуктов

HPMC vs Other
Эфиры целлюлозы

Cellulose ethers are a family of water-soluble polymers, each with distinct chemical structures and performance profiles. LANDERCOLL supplies HPMC, HEMC/MHEC, HEC, and CMC — the four most widely used in industrial formulation. Understanding the differences helps formulators select the most appropriate product.

HPMC
Гидроксипропилметилцеллюлоза
Неионогенные

Versatile water retention, thickening, film forming, workability, broad application compatibility.

Construction · Pharma · Food · Personal care · Detergents · Industrial
HEMC
Hydroxyethyl Methyl Cellulose (MHEC)
Неионогенные

Strong construction performance, excellent water retention, good anti-sag in drymix mortar.

Tile adhesive · Wall putty · Cement plaster · Gypsum · EIFS/ETICS
HEC
Гидроксиэтилцеллюлоза
Неионогенные

Excellent rheology control in aqueous systems, strong latex compatibility for coatings.

Water-based paints · Coatings · Cleaners · Personal care
CMC
Карбоэтилцеллюлоза
Анионный

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By Industry

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Construction grade
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Строительный Grade

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Detergent grade
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Гранулометрический Grade

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Personal care grade
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Градус для личной гигиены

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Pharmaceutical grade
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Food grade E464
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Food Grade (E464)

Compliant with applicable food additive regulations. Designed for food systems where texture control, water management, stabilization, and formulation consistency are required.

Bakery products · Sauces & dressings · Frozen food · Edible films · Texture-modified food · Vegan & halal applications
Industrial grade
Grade Direction · vi.
Industrial Grade

Designed for specialty industrial systems requiring thickening, binding, suspension stability, and process control across various non-food, non-pharma applications.

Ceramics processing · Construction adhesives · Textile printing · Paper-related systems · Specialty industrial fluids
Logistics & Documentation

Packaging, Storage & cURL Too many subrequests by single Worker invocation. To configure this limit, refer to https://developers.cloudflare.com/workers/wrangler/configuration/#limits

Упаковка и хранение

Packaging and Storage

LANDERCOLL HPMC is supplied in industrial packaging suitable for transportation, storage, and production handling. Cellulose ether powders are hygroscopic — proper storage conditions help maintain powder flowability, dissolution performance, and application effectiveness throughout product shelf life.

Standard Packaging

  • 25 kg per bag
  • Paper bag with inner moisture-protective polyethylene liner
  • Palletized packaging available upon request
  • Customized packaging options can be discussed for long-term supply cooperation

Storage Recommendations

  • Store in a cool, dry, and well-ventilated environment
  • Keep away from moisture, direct sunlight, and heat sources
  • Держите упаковку запечатанной, когда не используется
  • Избегайте загрязнений при обращении и транспортировке
  • Use within the recommended shelf life stated in product documentation
  • Do not store near strong oxidizing agents or reactive chemicals
Industrial packaging warehouse
Документация

Product Documentation
По запросу

LANDERCOLL can provide product-related documentation to support formulation evaluation, purchasing review, technical communication, regulatory submission, and internal approval processes.

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  • Технический паспорт (ТДС)
  • Инструкция по безопасности (SDS / MSDS)
  • Сертификат анализа (COA)
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  • Grade recommendation document
  • Packaging and storage specification
  • Export-related documentation, where applicable

All documentation is provided to help customers complete their internal evaluation, purchasing approval, and regulatory review processes efficiently. Contact our team to request specific documents for your application or market requirements.

Запросить документы на продукт
Inquiry Guide

How to Request the
Right HPMC Grade

To help our team recommend the most suitable HPMC grade for your application, please include as much of the following information as possible when contacting us. A detailed inquiry allows us to provide a more accurate grade recommendation and support your evaluation more efficiently.

i.
Application & Formulation System

Product application (e.g., tile adhesive, wall putty, shampoo, tablet coating) and formulation system type (cement-based, gypsum-based, liquid, semi-solid, other).

ii.
Current Grade or Viscosity Reference

Current HPMC grade or reference viscosity, if available. Main performance target — e.g., water retention, open time, viscosity level, texture, stability.

iii.
Testing Method & Quantity

Testing method or standard used, if applicable. Required quantity — sample, trial, or commercial volume.

iv.
Market & Documentation

Destination country or target market. Documentation requirements (TDS, SDS, COA, food/pharma compliance documents). Timeline for evaluation or sourcing decision.

ЧАСТО ЗАДАВАЕМЫЕ ВОПРОСЫ

Часто задаваемые вопросы
About HPMC

What is HPMC used for?

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Как выбрать правильный сорт HPMC?

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Почему LANDERCOLL

Почему выбирают ЛАНДЕРКОЛЛ HPMC

i.

Специализация в области целлюлозных эфиров

LANDERCOLL focuses on cellulose ether products — HPMC, HEMC/MHEC, HEC, and CMC. This product focus allows us to develop deeper application knowledge and provide more relevant technical support compared to general chemical distributors.

ii.

Application-Oriented Grade Matching

We help customers select HPMC based on real performance requirements — water retention, viscosity level, workability, open time, texture, stability, and processing behavior — rather than simply offering a product catalog.

iii.

Широкое покрытие отраслей

LANDERCOLL HPMC supports customers in construction materials, detergents, personal care, pharmaceuticals, food, coatings, ceramics, and specialty industrial sectors across multiple global markets.

iv.

Technical Documentation Support

We provide TDS, SDS, COA, product recommendation documents, and application guides to support your evaluation, purchasing review, and internal approval processes.

v.

Long-Term Supply Partnership

We aim to support customers from initial product inquiry through formulation testing, sourcing decisions, and long-term supply cooperation — with consistent product quality and responsive communication.

Связаться с нами

Find the Right HPMC Grade
для Ваше применение

LANDERCOLL HPMC supports manufacturers across construction materials, detergents, personal care, pharmaceuticals, food, coatings, ceramics, and specialty industrial applications. Whether you are developing a new formulation, optimizing an existing product, or evaluating a new cellulose ether supplier, our team can help you identify the most suitable grade and provide the documentation and technical support you need.

~ Ваш запрос · MMXXV ~
Продукт HPMC · CAS 9004-65-3
Приложение Ваша целевая формула
Grade Direction Low · Medium · High · XH
cURL Too many subrequests by single Worker invocation. To configure this limit, refer to https://developers.cloudflare.com/workers/wrangler/configuration/#limits Treated or non-treated
Документы TDS · SDS · COA
Рынок Страна и сегмент
Промышленность Construction · Pharma · Food · Care