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CAS 9004-65-3 · E464 EINECS 618-389-1

HPMC Hidroxipropilmetilcelulose

Definition, Chemistry, and Industrial Role — a complete reference for formulators across construction, pharma, food, personal care, and industrial sectors.

HPMC is a water-soluble, non-ionic cellulose ether produced by chemically modifying natural cellulose derived from wood pulp or cotton linter. It delivers multiple functional benefits — water retention, thickening, film forming, binding, and workability improvement — within a single versatile ingredient.

~ Quick Reference ~
Nome completo Hidroxipropilmetilcelulose
CAS No. 9004-65-3
Food Code cURL Too many subrequests by single Worker invocation. To configure this limit, refer to https://developers.cloudflare.com/workers/wrangler/configuration/#limits
Ionic Type Não-iónico
Solubilidade Cold water soluble
Pharma Name Hypromellose
Aparência Pó branco a esbranquiçado
Química
Cellulose ether chemistry lab
DS·MS Substitution
Lab analysis Chemical structure
What Is HPMC?

Definition, Chemistry,
e Industrial Role

HPMC is produced by reacting purified cellulose with methyl chloride and propylene oxide under controlled alkaline conditions. This process introduces two types of substituent groups onto the cellulose backbone, each influencing the final product's performance profile in different ways.

Methoxyl Groups (–OCH₃)

Control solubility, thermal gelation behavior, and surface activity of the cellulose ether.

Hydroxypropoxyl Groups

Influence water retention capacity, viscosity development, and compatibility with other ingredients.

The combination and ratio of these two substituents — expressed as degree of methyl substitution (DS) and molar substitution of hydroxypropyl (MS) — determine the grade's performance profile. Viscosity, measured at 2% aqueous solution using Brookfield or Ubbelohde methods, is the most commonly referenced parameter for grade selection, ranging from below 100 mPa·s to above 200,000 mPa·s depending on the grade.

Why HPMC Is Widely Used

HPMC is non-ionic — compatible with a wide range of additives, surfactants, salts, and pH conditions. It is also biodegradable, odorless, tasteless, and free from animal-derived raw materials, making it suitable for regulated and sensitive applications from drymix mortar to pharmaceutical excipients and food systems.

Dados Técnicos

HPMC Technical
Reference Data

The following table provides a general technical reference for Hydroxypropyl Methyl Cellulose. Exact values vary by product grade, viscosity level, substitution type, particle size, surface treatment, and testing method. This information is intended as a formulation reference starting point, not a final product specification.

ItemTypical Reference
Nome do produtoHidroxipropilmetilcelulose
AbbreviationHPMC
CAS No.9004-65-3
Food Additive CodecURL Too many subrequests by single Worker invocation. To configure this limit, refer to https://developers.cloudflare.com/workers/wrangler/configuration/#limits
AparênciaPó branco a esbranquiçado
Ionic TypeNão-iónico
Molecular BasisCellulose ether (modified natural cellulose)
Raw Material SourceWood pulp or cotton linter
SolubilidadeSoluble in cold water; insoluble in hot water above gelation temperature; forms viscous solution
Gelificação térmicaGels upon heating; re-dissolves upon cooling (thermally reversible)
Viscosity RangeMultiple grades: low / medium / high / extra-high viscosity
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Estabilidade do pHcURL Too many subrequests by single Worker invocation. To configure this limit, refer to https://developers.cloudflare.com/workers/wrangler/configuration/#limits
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Notas
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i.
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ii.
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Typically 5,000–50,000 mPa·s
Wall putty, skim coat, detergent, personal care, general industrial systems.
Texture · Viscosity building · Smooth workability
iii.
High Viscosity HPMC
Typically 50,000–150,000 mPa·s
Tile adhesive, cement plaster, gypsum plaster, drymix mortar systems.
Water retention · Open time · Workability
iv.
Extra High Viscosity HPMC
Typically above 150,000 mPa·s
High-performance tile adhesive, thick-layer mortar, vertical application systems.
Strong water retention · Anti-sag · Extended open time
v.
Grades by Surface Treatment
Treated or non-treated options
Surface-Treated

Delayed hydration — easier dispersion, reduced lumping, controlled dissolution. Preferred for drymix systems.

Non-Surface-Treated

Faster viscosity development — quick hydration, suitable for fast-dissolving and direct-hydration formulations.

Note: Viscosity ranges listed above are approximate references. Actual LANDERCOLL HPMC grades should be selected according to your formulation, testing method, application environment, and required documentation. Contact our team for specific grade recommendations.

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Key Functions of
HPMC in Formulation

HPMC is a multifunctional cellulose ether. In most applications, it contributes more than one functional benefit simultaneously. Below is a structured overview of its primary functions across different system types.

Retenção de água
i.
Retenção de água

In cement-based and gypsum-based systems, HPMC forms a polymer network that physically restricts water migration. Higher viscosity grades and higher dosage levels provide stronger water retention — preventing rapid water loss, incomplete hydration, and surface cracking.

Espessamento
ii.
Thickening & Viscosity Control

HPMC dissolves in cold water to form a viscous, pseudoplastic (shear-thinning) solution. Viscosity decreases under shear during mixing and recovers at rest — supporting both processability and in-place stability across drymix mortar, detergents, personal care, and coatings.

Trabalhabilidade
iii.
Melhoria da trabalhabilidade

In drymix construction materials, HPMC makes mortar smoother, more cohesive, and easier to spread, trowel, scrape, and finish. It is a combined result of water retention, viscosity building, and lubrication effects — particularly valued in tile adhesive, wall putty, and gypsum plaster.

iv.
Controle de Rendimento

Supports flow control, sag resistance, leveling behavior, and application stability. Prevents mortar from sliding on vertical surfaces, contributes to controlled flow in self-leveling compounds, and maintains stable viscosity in coatings and detergents.

v.
Formação de filmes

HPMC forms a continuous, flexible film after water evaporation — used in pharmaceutical tablet coating, edible film systems, construction surface integrity, and selected water-based coatings as a binder component.

vi.
Binding, Cohesion & Suspension

Supports structural integrity in tablet manufacturing, green strength in ceramics, and cohesion in drymix mortar. Also helps maintain uniform suspension of pigments, fillers, mineral powders, and active ingredients in coatings, detergents, and pharmaceutical systems.

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HPMC Application
Guia de Seleção

HPMC grade selection should always start from the application. A grade optimized for tile adhesive will not necessarily perform well in a detergent, personal care, or pharmaceutical system. The table below provides a structured reference for common application-to-grade matching.

AplicaçãoRecommended Grade DirectionPrincipais requisitos de desempenho
Adesivo para azulejosHigh to extra-high viscosityWater retention, open time, anti-slip, troweling feel
Massa de vidraceiro para paredes / revestimento de acabamentoMedium to high viscositySmooth scraping, water retention, surface finish
Reboco de cimento / estuqueMedium to high viscosityTrabalhabilidade, espalhabilidade, retenção de água
Reboco de gessoMedium to high viscosityAplicação suave, gestão de água, consistência
Compostos de auto-nivelamentoLow to medium viscosityFlow control, stability, controlled water retention
Argamassa para EIFS / ETICScURL Too many subrequests by single Worker invocation. To configure this limit, refer to https://developers.cloudflare.com/workers/wrangler/configuration/#limitscURL Too many subrequests by single Worker invocation. To configure this limit, refer to https://developers.cloudflare.com/workers/wrangler/configuration/#limits
Argamassa impermeávelMedium to high viscositycURL Too many subrequests by single Worker invocation. To configure this limit, refer to https://developers.cloudflare.com/workers/wrangler/configuration/#limits
Argamassa de alvenariaMedium to high viscositycURL Too many subrequests by single Worker invocation. To configure this limit, refer to https://developers.cloudflare.com/workers/wrangler/configuration/#limits
Argamassa de ReparoMedium to high viscositycURL Too many subrequests by single Worker invocation. To configure this limit, refer to https://developers.cloudflare.com/workers/wrangler/configuration/#limits
Detergente LíquidocURL Too many subrequests by single Worker invocation. To configure this limit, refer to https://developers.cloudflare.com/workers/wrangler/configuration/#limitscURL Too many subrequests by single Worker invocation. To configure this limit, refer to https://developers.cloudflare.com/workers/wrangler/configuration/#limits
Cuidados pessoaisLow to medium viscositycURL Too many subrequests by single Worker invocation. To configure this limit, refer to https://developers.cloudflare.com/workers/wrangler/configuration/#limits
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CerâmicaMedium to high viscositycURL Too many subrequests by single Worker invocation. To configure this limit, refer to https://developers.cloudflare.com/workers/wrangler/configuration/#limits
Revestimentos à Base de ÁguaLow to medium viscositycURL Too many subrequests by single Worker invocation. To configure this limit, refer to https://developers.cloudflare.com/workers/wrangler/configuration/#limits
cURL Too many subrequests by single Worker invocation. To configure this limit, refer to https://developers.cloudflare.com/workers/wrangler/configuration/#limitsMedium to high viscositycURL Too many subrequests by single Worker invocation. To configure this limit, refer to https://developers.cloudflare.com/workers/wrangler/configuration/#limits

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HPMC dosage depends on formulation design, raw material quality, target performance, ambient temperature, water quality, substrate type, and production process. The following ranges are general starting points for laboratory evaluation — not fixed usage standards.

For tile adhesive: 0.2%–0.5% is a widely referenced industry starting range. However, final dosage must be confirmed through laboratory testing and on-site performance evaluation, as substrate porosity, tile size, ambient temperature, and cement type all affect the optimal dosage.

Mortar application dosage
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Adesivo para azulejos0.2% – 0.5%
Massa de vidraceiro para paredes / revestimento de acabamento0.2% – 0.5%
Reboco de cimento / estuque0.15% – 0.4%
Reboco de gesso0.1% – 0.3%
Argamassa de alvenaria0.1% – 0.3%
Compostos de auto-nivelamento0.05% – 0.2%
Argamassa para EIFS / ETICS0.2% – 0.5%
Argamassa impermeável0.15% – 0.4%
Argamassa de Reparo0.15% – 0.4%
Detergente LíquidocURL Too many subrequests by single Worker invocation. To configure this limit, refer to https://developers.cloudflare.com/workers/wrangler/configuration/#limits
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Food / Pharma / SpecialtyDepends on grade, regulation, and formulation design

These dosage ranges are general starting points. Adjust based on testing results under your specific formulation, raw materials, and application conditions.

Aplicações

Construção &Argamassa Drymix

Construction is the largest and most established application area for HPMC globally — a critical additive for water retention, workability, open time, and anti-sag performance.

In drymix mortar systems, HPMC functions simultaneously as a water-retaining agent, rheology modifier, and workability enhancer. Without HPMC, cement-based and gypsum-based mortars tend to lose water too quickly to the substrate, resulting in poor hydration, weak bond strength, surface cracking, and difficult application.

Adesivo para azulejos

Water retention, open time extension, anti-slip behavior, and troweling feel. High to extra-high viscosity grades, 0.2%–0.5% dosage. Surface-treated grades commonly preferred.

Massa para paredes e Revestimento de acabamento

Scraping smoothness, water retention, surface finish quality. Medium to high viscosity, 0.2%–0.5% dosage.

Gypsum-Based Products

Controlled water retention without over-retarding set time. Smooth spreading, consistent texture, reduced surface defects. Medium to high viscosity grades.

Other Mortar Systems

Cement render, masonry mortar, self-leveling compounds, EIFS/ETICS, waterproof mortar, repair mortar, insulation mortar, joint fillers.

All Construction Applications
  • Adesivo para azulejos
  • Massas para paredes e camada de acabamento
  • Cement render & plaster
  • Reboco de gesso
  • Compostos autonivelantes
  • Argamassa para EIFS / ETICS
  • Argamassa impermeável
  • Argamassa de alvenaria
  • Argamassa de reparo
  • Argamassa de isolamento
  • Joint fillers
  • Ready-mix dry mortar systems
Aplicações

Home Care & Personal Care Formulações

Home care detergents Cuidados Domésticos & Detergentes

HPMC for Home Care
& Detergent Formulations

As a non-ionic polymer, HPMC is compatible with anionic and non-ionic surfactant systems commonly used in cleaning products. It builds smooth, stable viscosity that improves product appearance, pourability, and consumer perception — while helping maintain uniform suspension of insoluble components.

Aplicações Típicas

Laundry liquid Dishwashing liquid Toilet bowl cleaner Surface cleaner Gel cleaner Multi-purpose cleaner
  • Controlled viscosity and product body
  • Stable texture and appearance over shelf life
  • Improved pourability and handling feel
  • Suspension support for insoluble components
  • Compatible with common surfactant systems
Personal care products Cuidados pessoais

HPMC for Personal
Care Formulations

In personal care systems, HPMC functions as a viscosity modifier, texture enhancer, and formulation stabilizer. It is water-soluble, non-ionic, and free from animal-derived raw materials — making it suitable for a wide range of rinse-off and leave-on products where smooth, consistent texture and formulation stability across temperature and storage conditions are required.

Aplicações Típicas

Shampoo & conditioner Gel de banho Limpeza facial Hand soap Body lotion & cream Creme Dentário cURL Too many subrequests by single Worker invocation. To configure this limit, refer to https://developers.cloudflare.com/workers/wrangler/configuration/#limits cURL Too many subrequests by single Worker invocation. To configure this limit, refer to https://developers.cloudflare.com/workers/wrangler/configuration/#limits
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Farmacêutico

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Aplicações Típicas

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Aplicações Típicas

  • cURL Too many subrequests by single Worker invocation. To configure this limit, refer to https://developers.cloudflare.com/workers/wrangler/configuration/#limits
  • Sauces, dressings, and condiments
  • Frozen food systems (ice cream, frozen desserts)
  • Beverage systems
  • Edible film and coating applications
  • Vegetarian & vegan food products (gelatin alternative)
  • Thermal gelation: gels when heated, re-dissolves when cooled
  • Improved freeze-thaw stability
  • Suitable for vegetarian, vegan, and halal-compliant formulations

Food applications require suitable grade selection and compliance with applicable food regulations in the target market.

Discuss Food Grades
Coatings & Industrial

HPMC for Coatings and
Aplicações Industriais

HPMC can be used in selected water-based coatings and specialty industrial systems where thickening, film formation, binding, suspension control, and process stability are required. In architectural coatings, HEC is more commonly used as the primary cellulose ether thickener; however, HPMC can be suitable in specific coating formulations and industrial systems.

Key performance benefits include viscosity control and thickening, film formation and surface integrity, binding and cohesion in ceramic and industrial systems, suspension stability for pigments and fillers, and process consistency in extrusion and forming operations.

Industrial coatings application
Revestimentos à Base de Água

Selected architectural and decorative systems where HPMC's film-forming or thermal gelation properties offer a formulation advantage.

Revestimentos Texturizados

Decorative and texture coatings requiring stable viscosity, film formation, and consistent application behavior.

Construction Adhesives & Sealants

Binding, cohesion support, and process stability in adhesive and sealant formulations.

Ceramic Processing

Green body forming, extrusion, pressing — binding, green strength, and suspension support before firing.

Textile Printing Pastes

Viscosity control and rheology management in textile printing formulations.

Paper Coating & Sizing

Film formation, binding, and surface integrity in paper coating and sizing applications.

Specialty Industrial Fluids

Thickening, process control, and stability in specialty fluid formulations across various industrial sectors.

Agricultural Formulations

Viscosity building, suspension stability, and film formation in selected agricultural product systems.

Comparação de produtos

HPMC vs Other
Éteres de celulose

Cellulose ethers are a family of water-soluble polymers, each with distinct chemical structures and performance profiles. LANDERCOLL supplies HPMC, HEMC/MHEC, HEC, and CMC — the four most widely used in industrial formulation. Understanding the differences helps formulators select the most appropriate product.

HPMC
Hidroxipropilmetilcelulose
Não-iónico

Versatile water retention, thickening, film forming, workability, broad application compatibility.

Construction · Pharma · Food · Personal care · Detergents · Industrial
HEMC
Hydroxyethyl Methyl Cellulose (MHEC)
Não-iónico

Strong construction performance, excellent water retention, good anti-sag in drymix mortar.

Tile adhesive · Wall putty · Cement plaster · Gypsum · EIFS/ETICS
HEC
Hidroxietilcelulose
Não-iónico

Excellent rheology control in aqueous systems, strong latex compatibility for coatings.

Water-based paints · Coatings · Cleaners · Personal care
CMC
Carboximetilcelulose
Aniónico

Thickening, binding, stabilization, texture control; cost-effective across many systems.

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Construction grade
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Grau de Construção

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Detergent grade
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Grau de Detergente

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Personal care grade
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Grau de Cuidados Pessoais

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Pharmaceutical grade
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Food grade E464
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Food Grade (E464)

Compliant with applicable food additive regulations. Designed for food systems where texture control, water management, stabilization, and formulation consistency are required.

Bakery products · Sauces & dressings · Frozen food · Edible films · Texture-modified food · Vegan & halal applications
Industrial grade
Grade Direction · vi.
Industrial Grade

Designed for specialty industrial systems requiring thickening, binding, suspension stability, and process control across various non-food, non-pharma applications.

Ceramics processing · Construction adhesives · Textile printing · Paper-related systems · Specialty industrial fluids
Logistics & Documentation

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Embalagem e Armazenamento

Packaging and Storage

LANDERCOLL HPMC is supplied in industrial packaging suitable for transportation, storage, and production handling. Cellulose ether powders are hygroscopic — proper storage conditions help maintain powder flowability, dissolution performance, and application effectiveness throughout product shelf life.

Standard Packaging

  • 25 kg per bag
  • Paper bag with inner moisture-protective polyethylene liner
  • Palletized packaging available upon request
  • Customized packaging options can be discussed for long-term supply cooperation

Storage Recommendations

  • Store in a cool, dry, and well-ventilated environment
  • Keep away from moisture, direct sunlight, and heat sources
  • Manter a embalagem selada quando não estiver em uso
  • Evitar contaminação durante manuseio e transferência
  • Use within the recommended shelf life stated in product documentation
  • Do not store near strong oxidizing agents or reactive chemicals
Industrial packaging warehouse
Documentação

Product Documentation
Disponível mediante solicitação

LANDERCOLL can provide product-related documentation to support formulation evaluation, purchasing review, technical communication, regulatory submission, and internal approval processes.

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  • Ficha de Dados Técnicos (TDS)
  • Ficha de Dados de Segurança (FDS / MSDS)
  • Certificado de Análise (COA)
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  • Grade recommendation document
  • Packaging and storage specification
  • Export-related documentation, where applicable

All documentation is provided to help customers complete their internal evaluation, purchasing approval, and regulatory review processes efficiently. Contact our team to request specific documents for your application or market requirements.

Solicitar Documentos do Produto
Inquiry Guide

How to Request the
Right HPMC Grade

To help our team recommend the most suitable HPMC grade for your application, please include as much of the following information as possible when contacting us. A detailed inquiry allows us to provide a more accurate grade recommendation and support your evaluation more efficiently.

i.
Application & Formulation System

Product application (e.g., tile adhesive, wall putty, shampoo, tablet coating) and formulation system type (cement-based, gypsum-based, liquid, semi-solid, other).

ii.
Current Grade or Viscosity Reference

Current HPMC grade or reference viscosity, if available. Main performance target — e.g., water retention, open time, viscosity level, texture, stability.

iii.
Testing Method & Quantity

Testing method or standard used, if applicable. Required quantity — sample, trial, or commercial volume.

iv.
Market & Documentation

Destination country or target market. Documentation requirements (TDS, SDS, COA, food/pharma compliance documents). Timeline for evaluation or sourcing decision.

FAQ

Perguntas mais frequentes
About HPMC

What is HPMC used for?

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Como é que escolho o tipo certo de HPMC?

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Por que escolher a LANDERCOLL

Por que Escolher LANDERCOLL HPMC

i.

Especialização Focada em Éteres de Celulose

LANDERCOLL focuses on cellulose ether products — HPMC, HEMC/MHEC, HEC, and CMC. This product focus allows us to develop deeper application knowledge and provide more relevant technical support compared to general chemical distributors.

ii.

Application-Oriented Grade Matching

We help customers select HPMC based on real performance requirements — water retention, viscosity level, workability, open time, texture, stability, and processing behavior — rather than simply offering a product catalog.

iii.

Cobertura Ampla de Indústria

LANDERCOLL HPMC supports customers in construction materials, detergents, personal care, pharmaceuticals, food, coatings, ceramics, and specialty industrial sectors across multiple global markets.

iv.

Technical Documentation Support

We provide TDS, SDS, COA, product recommendation documents, and application guides to support your evaluation, purchasing review, and internal approval processes.

v.

Long-Term Supply Partnership

We aim to support customers from initial product inquiry through formulation testing, sourcing decisions, and long-term supply cooperation — with consistent product quality and responsive communication.

Entrar em contacto

Find the Right HPMC Grade
para A sua Aplicação

LANDERCOLL HPMC supports manufacturers across construction materials, detergents, personal care, pharmaceuticals, food, coatings, ceramics, and specialty industrial applications. Whether you are developing a new formulation, optimizing an existing product, or evaluating a new cellulose ether supplier, our team can help you identify the most suitable grade and provide the documentation and technical support you need.

~ A sua Consulta · MMXXV ~
Produto HPMC · CAS 9004-65-3
Aplicação A sua formulação alvo
Grade Direction Low · Medium · High · XH
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Documentos TDS · SDS · COA
Mercado País e segmento
Indústrias Construction · Pharma · Food · Care