GHS classification by the OSHA Hazard Communication Standard (29 CFR 1910.1200): Not a hazardous substance or mixture.
GHS Label Elements: Pictograms: N/A; Signal word: N/A.
Hazard and precautionary statements: None
Hazards not otherwise classified (HNOC) or not covered by GHS:None
Appearance: White to off-white powder
Odor: Odorless or slight characteristic odor
HPMC Full Form: Hydroxypropyl Methyl Cellulose
Solubility: Soluble in cold water (forms colloidal solution)
Viscosity: Varies by grade (e.g., 5–200,000 mPa·s at 20°C, 2% aqueous solution).
pH: ~6.0–8.0 (1% aqueous solution).
Stability:
Reactivity: Inert to most chemicals; avoid strong oxidizers (e.g., peroxides) and concentrated acids/bases.
Acute Toxicity:
Oral (LD50): >5,000 mg/kg (rat, OECD 423) – Practically non-toxic (GHS Category 5 or unclassified).
Dermal/Irritation: Non-irritation to the skin (OECD 404); mild eye irritation (OECD 405).
Inhalation (LC50): Not applicable (low dustiness, non-volatile).
Sensitization:No evidence of skin sensitization (OECD 406).
Chronic Effects:
No carcinogenicity (IARC/EPA unlisted), no reproductive toxicity.
Prolonged dust inhalation may cause respiratory irritation (mechanical effect).
Biodegradability:
Readily biodegradable (OECD 301B, >60% in 28 days).
Ecotoxicity:
Aquatic: LC50 (Daphnia magna) >100 mg/L – Low toxicity (GHS unclassified).
Terrestrial: No significant effects on soil organisms.
Environmental Fate:
Degrades via microbial action; no bioaccumulation (log Kow: -2.5).
OELs:
Not established (low hazard); general dust limit (e.g., 10 mg/m³ total dust).
Engineering Controls:
Local exhaust ventilation for powder handling.
Personal Protective Equipment：
Gloves: Nitrile or latex (minimal risk).
Eye Protection: Safety goggles if dust generation is possible.
Respirator: N95 mask for prolonged high-dust operations.
Personal precautions, protective equipment, and emergency procedures:
Avoid dust formation. Avoid breathing vapors, mist, or gas.
Environmental precautions: Do not let the product enter drains.
Methods and materials for containment and cleaning up:
Sweep up and shovel. Keep in suitable, closed containers for disposal.
Suitable extinguishing media: Use water spray, CO₂, or dry chemicals;
Special hazards arising from the substance or mixture: Carbon oxides
Advice for firefighters: Use a self-contained breathing apparatus (SCBA) for firefighting when required.
Inhalation: Move to fresh air.
Eye/Skin contact: Rinse with water for 15 minutes.
Ingestion: Rinse mouth; drink water (no induced vomiting).
Storage condition: Dry (<60% RH), closely sealed
Recommended storage temperature:Recommended storage temperature see product label.
More information on storage stability: Keep away from incompatible materials (oxidizers).
Precautions for safe handling: Provide appropriate exhaust ventilation at places where dust is formed.
Classification: Non-hazardous waste in most regions.
Disposal Methods: Landfill or incineration (follow local regulations) following the national and local regulations.
GHS Label : None required (non-hazardous per most jurisdictions).
Standards:
FDA: 21 CFR 172.874 (food-grade approved).
EU: REACH registered; E464 (food additive).
China: GB 1886.102-2016 (food safety standard).
The information provided herein is based on current scientific knowledge and industry best practices regarding the handling and disposal of HPMC (Hydroxypropyl Methylcellulose). While every effort has been made to ensure accuracy, this guidance is not exhaustive and should be treated as a general reference only.
The recommendations outlined are specific to the product under standard conditions and assume adherence to proper safety measures. However, actual conditions of use may vary, and users must evaluate applicability based on their specific circumstances.
No express or implied warranty is made concerning the product’s properties, performance, or suitability for any particular purpose. The recipient assumes all responsibility for verifying regulatory compliance and implementing appropriate risk controls.
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Deutsch 
Українська 
Ελληνικά 
Español 
Español de Perú 
Français 
Magyar 
Bahasa Indonesia 
Italiano 
Português 
Türkçe 
Русский 
Nederlands 
Slovenčina 
Svenska 
Български 
Čeština 
Dansk 
Eesti 
Suomi 
日本語 
한국어 
Lietuvių kalba 
Latviešu valoda 
Norsk bokmål 
Polski 
Português do Brasil 
Română 
Slovenščina